The third edition of "Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012​" appeared in the February 2013 issues of Critical Care Medicine and Intensive Care Medicine.

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012​​
Complete Implementation and Improvement Guide

Tables summarizing the recommendations can be a useful tool in clinical settings.

Initial Resuscitation and Infection Issues 
Hemodynamic Support and Adjunctive Therap​y
Other Supportive Therapy of Severe Sepsis
Special Considerations in Pediatrics​​


 SSC Statements



The Campaign has received many inquiries regarding the recent publication of the Protocol-Based Care for Early Septic Shock (ProCESS) trial’s effect on the continuing activities of the Campaign.The Campaign looks forward to additional evidence regarding the optimal resuscitation of patients with severe sepsis and septic shock. Given the existing evidence supporting early targeted resuscitation in these patients, SSC continues to recommend all elements of the current bundles.
Surviving Sepsis Campaign Responds to ProCESS Trial - March 28, 2017

After review of evidence, discussion of practice patterns, and emphasis of the need for early recognition of sepsis, the SSC leadership re-confirmed the use of triage time as “time zero” in the emergency department.
Statement from SSC Leadership on Time Zero in the Emergency Department.

In response to comments and questions, the SSC leadership has provided additional background regarding the guideline recommendation regarding measurement of CVP, ScvO2, and lactate.
Statement from the SCC Leadership on CVP, ScvO2, and Lactate Measurements.


 Guideline Translations


The Surviving Sepsis Campaign is committed to reducing mortality from severe sepsis and septic shock worldwide. The Guidelines have been translated into several languages.

Chinese Guidelines Translation
French Guidelines Translation
German Guidelines Translation
Japanese Guidelines Translation
Persian Guidelines Translation
Portuguese Guidelines Translation
Spanish Guidelines Translation